A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative Colitis

This study will look at how safe and tolerable different treatments are for adults who have moderate to severe ulcerative colitis (UC). The platform design uses one single master protocol that explains how the overall study is organized, whereas each treatment, as sub-study will be tested to see how well the study drug works and how it affects participants.

NCT Number	NCT07747467
Lead Sponsor	GlaxoSmithKline
Conditions	Colitis, Ulcerative
Enrollment	16 participants
Start Date	2026-08-10
Primary Completion	2028-07-31 (estimated)
Study Completion	2028-12-04 (estimated)
Updated on ClinicalTrials.gov	2026-08-05