Digital Phenotyping of Psychological Distress in Skin Cancer Patients

This prospective observational study enrolls 500 skin cancer patients across five Chinese tertiary care centers. The investigators use natural language processing and a hierarchical transformer model to analyse 1.2 million social media posts (Weibo, Douyin, Xiaohongshu, WeChat) for psychological distress and suicide ideation, with prospective validation of an AI Early Warning System.

NCT Number	NCT07670403
Lead Sponsor	West China Hospital
Conditions	Skin Cancer, Melanoma (Skin Cancer), Squamous Cell Carcinoma Head and Neck Cancer (HNSCC), Basal Cell Carcinoma of Skin
Enrollment	500 participants
Start Date	2024-01-01
Primary Completion	2025-12-30 (estimated)
Study Completion	2026-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-26