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A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung Cancer

Name: A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung Cancer — clinical trial record (NCT07669779)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhasePhase 2

SponsorAkeso

Started2026-07-10

View on ClinicalTrials.gov ↗

Amendment history

2026-07-13

Study Status, Contacts/Locations v1

Recruitment opened

Start dateestimated 2026-06-30→confirmed 2026-07-10

Study sitesdetails revised at 1 of 1 site

2026-06-21

Original filing

Akeso

96 trials monitored

See 1 trial at risk

Lung Cancer

4,033 trials monitored

See 210 trials at risk

Non-Small Cell Lung Cancer (NSCLC)

2,914 trials monitored

See 156 trials at risk

This is a phase II clinical study evaluating the safety, tolerability, pharmacokinetics and antitumor efficacy of AK146D1 in combination with AK112 or other anticancer therapies in patients with advanced Non-Small Cell Lung Cancer.

Trial Details

NCT Number	NCT07669779
Lead Sponsor	Akeso
Conditions	Advanced Non Small Cell Lung Cancer (NSCLC)
Enrollment	348 participants
Start Date	2026-07-10
Primary Completion	2027-08-30 (estimated)
Study Completion	2029-05-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-14