HFpEF Phenotyping With Echo, Clinical, and Biomarkers

The EPIC-HFpEF registry is a nationwide Italian study that follows people with a specific type of heart failure called HFpEF. About 500 patients will be enrolled from several specialized hospitals and monitored for up to two years, without changing their usual treatment. The goal is to better understand this complex condition by identifying different patient "types" based on clinical features, heart imaging, and blood markers. Researchers will also look at how these groups are treated in real life and how their disease progresses over time. By doing this, the study aims to improve how doctors classify and manage HFpEF, moving toward more personalized and effective care for patients in the future.

NCT Number	NCT07642921
Lead Sponsor	University Of Perugia Collaborators: Azienda Ospedaliera di Perugia, Ospedale Le Scotte, University of Foggia
Conditions	Heart Failure With Preserved Ejection Fraction (HFPEF)
Enrollment	500 participants
Start Date	2026-06-02
Primary Completion	2027-06-30 (estimated)
Study Completion	2029-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-11