Clinical Trial

Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Depressive Symptoms in Patients With Parkinson's Disease

Enrolling by Invitation
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Summary
The purpose of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) in improving depressive symptoms in patients with Parkinson's Disease (PD). Participants will be randomly assigned to either an active rTMS group or a sham-control group. The study aims to establish an optimal treatment protocol using a neuronavigation system and to validate treatment responses through various digital biomarkers such as facial expression analysis and eye-tracking.
Protocol Amendment History 1 change
critical Primary endpoint(s) modified 2026-08-06
Trial Details
NCT Number NCT07569133
Lead Sponsor Ho-Won Lee
Collaborators: Korea Brain Research Institute
Conditions Parkinson's Disease, Depression
Enrollment 50 participants
Start Date 2026-05-04
Primary Completion 2026-10-23 (estimated)
Study Completion 2026-10-23 (estimated)
Updated on ClinicalTrials.gov 2026-08-05