Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Depressive Symptoms in Patients With Parkinson's Disease

StatusEnrolling by Invitation
PhaseNot applicable
SponsorHo-Won Lee
Started

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Trial flagged as At Risk
Primary completion moved at least 35 days later Oct 23, 2026 → Nov 27, 2026
Primary endpoint reworded 2 of 2 changed
Primary endpoint reworded 2 of 2 changed
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Record History

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  1. Primary endpoint(s) modified Show 5 more changesShow less
    • Primary completion pushed from Oct 23, 2026 to Nov 27, 2026
    • Study completion pushed from Oct 23, 2026 to Dec 31, 2026
    • Eligibility criteria expanded, about 58 words
    • Secondary endpoints: 12 to 14
    • Study description expanded, about 67 words
  2. Primary endpoint(s) modified
    • Secondary endpoints revised (12)
    v2
  3. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Ho-Won Lee
1 trial monitored
See 1 trial at risk
Depression
3,069 trials monitored
See 170 trials at risk
Parkinson's Disease
1,462 trials monitored
See 71 trials at risk
The purpose of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) in improving depressive symptoms in patients with Parkinson's Disease(PD). Participants will be randomly assigned to either an active rTMS group or a sham-control group. The study aims to evaluate the efficacy and feasibility of a neuronavigation-guided bilateral M1 rTMS protocol.
Trial Details
NCT Number NCT07569133
Lead Sponsor Ho-Won Lee
Collaborators: Korea Brain Research Institute
Conditions
(from sponsor)		 Parkinson's Disease, Depression
Related terms Depression, Nerve Degeneration, Parkinson Disease
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov