Clinical Trial

Assessment of Biosignature Classification of DCIS for RadioTherapy Benefit Post Lumpectomy (ABCD RT)

Name: Assessment of Biosignature Classification of DCIS for RadioTherapy Benefit Post Lumpectomy (ABCD RT) — clinical trial record (NCT07554573)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: ABCD RT

Not Yet Recruiting Phase 3

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Summary

NRG-CC016 is being done to determine if omission of radiation therapy (RT) for patients with biosignature Low Risk (DCISionRT score less than 2.8) DCIS yields no clinically meaningful increase ipsilateral breast recurrence (IBR) compared to those treated with RT (Cohort A).

Trial Details

NCT Number	NCT07554573
Lead Sponsor	NRG Oncology Collaborators: National Cancer Institute (NCI)
Conditions	Breast Cancer
Enrollment	5,270 participants
Start Date	2026-06-30
Primary Completion	2039-07-31 (estimated)
Study Completion	2048-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-28