Clinical Trial

Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases

Active, Not Recruiting
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Summary
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real world data analyses can be conducted with confidence and how to implement such studies.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2026-03-16; most recent amendment 2026-05-07.
Trial Details
NCT Number NCT07485179
Lead Sponsor Brigham and Women's Hospital
Collaborators: Food and Drug Administration (FDA)
Conditions Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Enrollment 770 participants
Start Date 2026-03-12
Primary Completion 2026-09-12 (estimated)
Study Completion 2027-03-12 (estimated)
Updated on ClinicalTrials.gov 2026-05-12