Emulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic Health Records Databases

Investigators are building an empirical evidence base for real-world data through large-scale emulation of randomized controlled trials. The investigators' goal is to understand for what types of clinical questions real-world data analyses can be conducted with confidence and how to implement such studies.

NCT Number	NCT07485166
Lead Sponsor	Brigham and Women's Hospital Collaborators: Food and Drug Administration (FDA)
Conditions	Advanced Non-squamous Non-small-cell Lung Cancer, Advanced Squamous Non Small Cell Lung Cancer
Enrollment	810 participants
Start Date	2026-03-12
Primary Completion	2026-09-12 (estimated)
Study Completion	2027-03-12 (estimated)
Updated on ClinicalTrials.gov	2026-05-08