Improved Management of Patients With Recent-Onset Stable Chest Pain

In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused. The IMPRO stepped-wedge trial tests a new, nationwide care model (NVF) in 16 regions to improve guideline-based intersectoral implementation of coronary CT and assess its impact on cardiovascular outcomes and healthcare costs. If effective, the model of care (NVF) could be adopted across Germany to enhance care quality while reducing unnecessary procedures and expenses.

NCT Number	NCT07476040
Lead Sponsor	Philipps University Marburg Collaborators: Gemeinsamer Bundesaussschuss
Conditions	Coronary Artery Disease (CAD)
Enrollment	3,369 participants
Start Date	2026-04-01
Primary Completion	2028-03 (estimated)
Study Completion	2028-03 (estimated)
Updated on ClinicalTrials.gov	2026-04-07