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Improved Management of Patients With Recent-Onset Stable Chest Pain

Study acronym: IMPRO
StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Recruitment opened
    • Start date changed from estimate of Apr 2026 to Apr 1, 2026
    • Secondary endpoints: 18 to 20
    • Site details revised at 39 of 39 sites
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused. The IMPRO stepped-wedge trial tests a new, nationwide care model (NVF) in 16 regions to improve guideline-based intersectoral implementation of coronary CT and assess its impact on cardiovascular outcomes and healthcare costs. If effective, the model of care (NVF) could be adopted across Germany to enhance care quality while reducing unnecessary procedures and expenses.
Trial Details
NCT Number NCT07476040
Lead Sponsor Philipps University Marburg
Collaborators: Gemeinsamer Bundesaussschuss
Conditions
(from sponsor)		 Coronary Artery Disease (CAD)
Related terms Coronary Artery Disease, Coronary Disease
Enrollment 3,369 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov