Clinical Trial

SWITCH: Apixaban vs Vitamin K in HM3

Not Yet Recruiting Phase 3
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Summary
This study is being done to learn the safety and efficacy of a new anticoagulant therapy with apixaban as compared to warfarin to prevent thrombotic events while protecting from bleeding complications in patients with advanced heart failure who are chronically supported by a HeartMate 3 Left Ventricular Assist Device for 3 months.
Trial Details
NCT Number NCT07471139
Lead Sponsor Columbia University
Conditions LVAD (Left Ventricular Assist Device) Thrombosis, Heart Failure, Bleeding, Thrombosis; Artery, Stroke, Heart Transplant
Enrollment 460 participants
Start Date 2026-06
Primary Completion 2029-06 (estimated)
Study Completion 2029-06 (estimated)
Updated on ClinicalTrials.gov 2026-03-13