Clinical Trial

The Impact of Continuous Glucose Monitoring on Glucose Variability and Weight Loss in Individuals With Prediabetes and Obesity

Study acronym: CGM
Recruiting
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Summary
This randomized, crossover interventional study evaluates the effects of real-time (open) versus blinded continuous glucose monitoring (CGM) on glycemic variability, lifestyle behaviors, and metabolic outcomes in adults with prediabetes and overweight or obesity (BMI ≥ 27 kg/m²). Thirty participants will undergo both open and blinded CGM phases, separated by a washout period. The study aims to assess whether access to real-time glucose data promotes behavioral change and improves metabolic health compared with blinded CGM use.
Protocol Amendment History 3 changes
critical Recruitment opened 2026-04-29
notable Primary completion pushed: 2026-12-01 -> 2027-04-01 2026-04-29
minor Completion pushed: 2027-06-01 -> 2027-09-01 2026-04-29
Trial Details
NCT Number NCT07423065
Lead Sponsor University of Primorska
Collaborators: Diabetes Outpatient Clinic, Community Health Center Koper, Slovenia, University Medical Centre Ljubljana
Conditions Pre Diabetic, Obesity & Overweight
Enrollment 34 participants
Start Date 2026-09-01
Primary Completion 2027-04-01 (estimated)
Study Completion 2027-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-28