Clinical Trial

Wellbeing and Survival Improvement With Event Reduction by Ablation for Atrial Fibrillation in the Very Elderly

Study acronym: WISER-AF
Recruiting
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Summary
The WISER-AF trial is a multicenter, double-blind, sham-controlled, randomized controlled trial. It aims to evaluate the efficacy and safety of catheter ablation compared to a sham procedure in improving the quality of life (SF-36 score) in very elderly patients (aged ≥80 years) with symptomatic atrial fibrillation over a 6-month follow-up period.
Protocol Amendment History 1 change
notable Enrollment reduced: 182 -> 136 participants 2026-07-07
Trial Details
NCT Number NCT07403760
Lead Sponsor Beijing Anzhen Hospital
Conditions Atrial Fibrillation (AF)
Enrollment 136 participants
Start Date 2026-07-01
Primary Completion 2028-11-30 (estimated)
Study Completion 2028-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-06