Restrictive Versus Liberal Fluid Intake in Acute Decompensated Heart Failure

The aim of this clinical trial is to learn whether a thirst-driven, liberal fluid-intake strategy is comparable to a fluid-restriction strategy in patients hospitalized for acute decompensated heart failure (ADHF). The study will also assess the safety of the intervention and its effects on thirst and quality of life. Patients hospitalized with ADHF will be asked to follow either a thirst-driven fluid-intake strategy or a fluid-restriction strategy during their hospital stay and for one month after discharge.

NCT Number	NCT07400991
Lead Sponsor	Gødstrup Hospital
Conditions	Acute Heart Failure (AHF)
Enrollment	420 participants
Start Date	2026-05-01
Primary Completion	2029-05-01 (estimated)
Study Completion	2029-08 (estimated)
Updated on ClinicalTrials.gov	2026-05-07