Clinical Trial

A Clinical Study of MK-4082 in Healthy Overweight Participants (MK-4082-002)

Active, Not Recruiting Phase 1
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Summary
Researchers are looking for new weight loss medicines for people with higher body weight. The study medicine, MK-4082, is different from similar weight loss medicines because people take it as a pill instead of an injection. Before giving a study medicine to people with a health condition, researchers first do studies to find a safe dose level (amount) of the study medicine that can be used in future studies. The goals of this study are to learn about: * The safety of MK-4082 and if people tolerate it * What happens to different MK-4082 dose levels in a person's body over time
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-05-29
Trial Details
NCT Number NCT07388667
Lead Sponsor Merck Sharp & Dohme LLC
Conditions Healthy
Enrollment 120 participants
Start Date 2026-03-04
Primary Completion 2026-09-02 (estimated)
Study Completion 2026-09-09 (estimated)
Updated on ClinicalTrials.gov 2026-06-16