Clinical Trial

Multimodal Analysis of Endomyocardial Biopsies

Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and therapy. The main aim is: -Identification of molecular profiles (e.g., proteome, lipidome, metabolome) and immune signalling profiles that are specifically associated with different myocardial diseases and the post-heart transplantation course. Participants already receiving an endomyocardial biopsy as part of their regular medical care will be enrolled. An additional biopsy sample will be taken for the above mentioned research.
Trial Details
NCT Number NCT07359690
Lead Sponsor University Hospital, Essen
Conditions Heart Transplantation, Dilated Cardiomyopathy (DCM), Hypertrophic Cardiomyopathy (HCM), Myocarditis, Pericarditis, Amyloidosis Cardiac, Cardiomyopathies, Sarcoidosis of the Heart
Enrollment 216 participants
Start Date 2025-10-27
Primary Completion 2028-09-30 (estimated)
Study Completion 2028-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-22