Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended

Coronary artery disease, or narrowing of the blood vessels that provide blood to the heart, is the most common cause of death in the United States and can be treated with either coronary bypass surgery or coronary stent placement. This study will evaluate outcomes, including death and quality of life, at 10 years in 1,500 patients with coronary disease who have already been randomized to either bypass surgery or stenting.

NCT Number	NCT07308860
Lead Sponsor	Stanford University Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions	Coronary Artery Disease
Enrollment	1,500 participants
Start Date	2025-08-01
Primary Completion	2030-06-30 (estimated)
Study Completion	2030-06-30 (estimated)
Updated on ClinicalTrials.gov	2025-12-30