Clinical Trial

The Effects of Dietary Nitrate in Patients With Hypertensive Kidney Injury

Study acronym: DINO-CKD
Recruiting
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Summary
The study aims to study the effects of diatery nitrate in patients with hypertension and hypertensive kidney injury. The study is a randomized, placebo-controlled, double-blinded crossover trial. 14-20 patients with hypertension and CKD I-III will be randomized to receive either nitrate or placebo delivered in the form of beetroot juice. Effect variables will be measured before and after a 2 week treatment. After a washout period of 14 days, the subjects are crossed over to the opposite treatment. The study is terminated by measuring effect variables after the second treatment period.
Trial Details
NCT Number NCT07290842
Lead Sponsor Gødstrup Hospital
Conditions Hypertension, CKD - Chronic Kidney Disease
Enrollment 20 participants
Start Date 2025-12-08
Primary Completion 2028-01-01 (estimated)
Study Completion 2030-01-01 (estimated)
Updated on ClinicalTrials.gov 2025-12-18