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A Study to Investigate Mocertatug Rezetecan Compared With Chemotherapy in Participants With Endometrial Cancer After Platinum-based Chemotherapy and Immunotherapy (BEHOLD-Endometrial01)

StatusRecruiting
PhasePhase 3
Started2026-06-04
View on ClinicalTrials.gov ↗
This study specifically aims to evaluate how well mocertatug rezetecan (Mo-Rez) works in treating Endometrial Cancer (EC) compared to standard of care. The study also assesses whether Mo-Rez is safe and tolerated well by participants in comparison to standard of care and will help provide a better understanding of the main side effects of the drugs.

Amendment history 4 changes detected by DataLookout

2026-09-01
minor
Trial sites expanded: 18 → 28 locations
2026-07-16
minor
Trial sites expanded: 14 → 18 locations
2026-07-03
notable
Recruitment opened
2026-07-03
minor
Trial sites expanded: 0 → 14 locations
Trial Details
NCT Number NCT07286331
Lead Sponsor GlaxoSmithKline
Collaborators: ENGOT, GOG, APGOT
Conditions Neoplasms, Endometrial
Enrollment 600 participants
Start Date 2026-06-04
Primary Completion 2028-02-29 (estimated)
Study Completion 2029-05-30 (estimated)
Updated on ClinicalTrials.gov 2026-08-31