Clinical Trial

Effect of Maridebart Cafraglutide on the Heart's Electrical Activity

Active, Not Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
The main objective of this trial is to evaluate the effect of maridebart cafraglutide subcutaneously (SC) on the placebo-corrected, change from baseline in QT interval corrected for heart rate using Fridericia's formula in participants living with overweight or obesity.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-11-13; most recent amendment 2026-01-22.
Status change: Recruiting → Active, Not Recruiting 2026-01-22
Status change: Not Yet Recruiting → Recruiting 2025-11-25
Trial Details
NCT Number NCT07229157
Lead Sponsor Amgen
Conditions Overweight, Obesity
Enrollment 81 participants
Start Date 2025-10-22
Primary Completion 2026-08-26 (estimated)
Study Completion 2026-08-26 (estimated)
Updated on ClinicalTrials.gov 2026-01-23