Clinical Trial

AZD0486 1L Therapy for Elderly or Unfit Participants With LBCL

Study acronym: SOUNDTRACK-D2
Recruiting Phase 3
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Summary
The purpose of this study is to measure the efficacy and safety of R-mini-CHOP × 2 followed by AZD0486 compared with R-mini-CHOP × 6 in elderly or unfit participants newly diagnosed with LBCL.
Protocol Amendment History 2 changes
notable Trial sites expanded: 64 -> 68 locations 2026-06-19
notable Trial sites expanded: 45 -> 62 locations 2026-04-22
Trial Details
NCT Number NCT07215585
Lead Sponsor AstraZeneca
Conditions Large B-cell Lymphoma
Enrollment 420 participants
Start Date 2025-11-11
Primary Completion 2030-06-10 (estimated)
Study Completion 2033-07-28 (estimated)
Updated on ClinicalTrials.gov 2026-06-18