Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days

Veterans with posttraumatic stress disorder (PTSD) need more effective treatments. Existing options can have limited adherence and can be very time-consuming. As such, alternative interventions are needed. Transcranial magnetic stimulation (TMS) has been FDA-cleared for depression since 2008 and has recently been cleared to treat smoking cessation and obsessive-compulsive disorder. It has demonstrated promise for reducing PTSD symptom severity but standard TMS has a significant time requirement. This study will compare an accelerated 5-day form of TMS versus sham for PTSD, characterizing efficacy and durability. This project will provide important information that can be implemented in the near term for Veterans with PTSD.

NCT Number	NCT07167940
Lead Sponsor	VA Office of Research and Development
Conditions	PTSD
Enrollment	90 participants
Start Date	2026-10-01
Primary Completion	2030-09-30 (estimated)
Study Completion	2030-12-06 (estimated)
Updated on ClinicalTrials.gov	2026-07-29