Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

This study is for adult patients with head and neck cancer who are at risk of recurrence. The purpose of this study is to evaluate whether the use of Indocyanine Green (ICG) dye allows for better identification of tumor tissue during surgical procedures. Participation will include standard of care visits along with administration of ICG dye and imaging during surgery. Participation in this study will last approximately 6 weeks.

NCT Number	NCT07149207
Lead Sponsor	Medical University of South Carolina
Conditions	Squamous Cell Carcinoma Head and Neck Cancer (HNSCC), Margin Assessment
Enrollment	30 participants
Start Date	2026-05-04
Primary Completion	2028-04-07 (estimated)
Study Completion	2029-04-07 (estimated)
Updated on ClinicalTrials.gov	2026-07-07