Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation Therapy

A randomized controlled trial to assess the impact of prophylactic proton pump inhibitor use to improve esophagitis in lung cancer patients undergoing radiation. Patients will be randomized into a standard of care arm or the prophylactic proton pump (daily) arm.

NCT Number	NCT07076914
Lead Sponsor	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions	Primary Lung Cancer, Non Small Cell Lung Cancer, Small Cell Lung Cancer
Enrollment	58 participants
Start Date	2025-10-02
Primary Completion	2028-01-02 (estimated)
Study Completion	2032-10-02 (estimated)
Updated on ClinicalTrials.gov	2025-07-22