An ISO Principle-Based Music Intervention for Reducing Stress, Anxiety, and Depression

This study aims to evaluate the effectiveness of a music-based intervention, guided by the ISO principle, in reducing stress, anxiety and depression induced by work, family or others among adults. The ISO principle suggests that emotional regulation can be supported by gradually modifying the emotional characteristics of music to help individuals transition to a desired emotional state. Participants in this study will be randomly assigned to either a music intervention group or a control group. The intervention group will receive personalized music playlists designed to help reduce stress, anxiety and depression. The control group will not receive any music intervention during the same period. Outcomes will be measured using self-report questionnaires assessing stress, emotional state, and well-being. The study is designed to contribute to the development of accessible, non-invasive stress management tools using music as a behavioral intervention.

NCT Number	NCT07055061
Lead Sponsor	Shanghai Mental Health Center Collaborators: Tsinghua University
Conditions	Stress, Anxiety, Depression in Adults
Enrollment	2,000 participants
Start Date	2024-04-23
Primary Completion	2026-08-30 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-23