Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07040280 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Sulforaphane for the Prevention of Melanoma in Patients With Multiple Atypical Nevi and a Prior History of Melanoma

StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 2 years 1 month later Feb 1, 2029 → Mar 1, 2031
Primary endpoint reworded 1 of 1 changed
See other at-risk trials from ECOG-ACRIN Cancer Research Group

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion pushed from Feb 1, 2029 to Mar 1, 2031 Show 12 more changesShow less
    • Primary endpoint(s) modified
    • Sponsor changed: Eastern Cooperative Oncology Group to ECOG-ACRIN Cancer Research Group
    • Recruitment opened
    • Start date changed from estimate of Oct 31, 2025 to Feb 20, 2026
    • Study completion pushed from Aug 1, 2029 to Mar 1, 2033
    • Interventions modified
    • Eligibility criteria expanded, about 176 words
    • Secondary endpoints revised (2)
    • Study description expanded, about 372 words
    • Site details revised
    • Collaborators shortened, about 5 words
    • Study title shortened, about 5 words
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This phase II trial tests how well sulforaphane works in preventing melanoma in patients with multiple atypical moles (nevi) and a prior history of melanoma. Patients with a history of melanoma and multiple atypical nevi are at a significantly increased risk of developing additional melanomas than those without atypical nevi. Prevention measures usually include sun protection, monthly skin self-examinations and regular skin examinations from a doctor. Sulforaphane is a naturally-occurring substance found in many cruciferous vegetables, including broccoli, that may prevent melanoma from forming.
Trial Details
NCT Number NCT07040280
Lead Sponsor ECOG-ACRIN Cancer Research Group
Conditions
(from sponsor)		 Clinical Stage 0 Cutaneous Melanoma AJCC v8, Clinical Stage I Cutaneous Melanoma AJCC v8, Clinical Stage II Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Melanoma AJCC v8, Cutaneous Dysplastic Nevus
Enrollment 120 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov