A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

StatusRecruiting
PhasePhase 2
SponsorPfizer
Started

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Trial flagged as At Risk
Primary completion moved at least 5 months later Nov 16, 2027 → May 8, 2028
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Record History

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  1. Primary completion pushed from Nov 16, 2027 to May 8, 2028 Show 4 more changesShow less
    • Trial sites expanded: 142 → 150 locations
    • Study completion pushed from Dec 14, 2027 to Jun 5, 2028
    • Eligibility criteria expanded, about 10 words
    • Secondary endpoints: details revised at 5 of 6 entries
  2. Study sites: 141 to 142v16
  3. Study sites: 139 to 141v15
  4. Trial sites expanded: 135 → 139 locationsv14
  5. Site details revised at 4 of 135 sitesv13
Show 4 earlier versionsHide 4 earlier versions
  1. Study sites: 133 to 135v12
  2. Study sites: 132 to 133v11
  3. Study sites: 131 to 132v10
  4. Study sites: 130 to 131v9
  1. Trial sites expanded: 125 → 130 locations
    • Site details revised at 7 of 130 sites
    v8
  2. Study sites: 125 to 130v7
  3. Study sites: 116 to 125v6
  4. Study sites: 95 to 116v5
  5. Study sites: 24 to 95
    • Eligibility criteria shortened, about 7 words
    v4
  6. Study sites: 5 to 24v3
  7. Trial status: Not Yet Recruiting to Recruitingv2 Show 4 more changesShow less
    • Study sites: 0 to 5
    • Primary completion date: Nov 2, 2027 to Nov 16, 2027
    • Study completion date: Nov 30, 2027 to Dec 14, 2027
    • Start date changed from estimate of Jun 5, 2025 to Jun 19, 2025
  8. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Pfizer
441 trials monitored
See 31 trials at risk
Heart Disease
8,870 trials monitored
See 440 trials at risk
Heart Failure
2,017 trials monitored
See 121 trials at risk
The purpose of this study is to learn about the safety and effects of the study medicine (PF-07328948) for the possible treatment of heart failure (HF).
Trial Details
NCT Number NCT06991257
Lead Sponsor Pfizer
Conditions
(from sponsor)		 Heart Failure
Related terms Heart Failure
Enrollment 620 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov