Clinical Trial

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

Study acronym: COLOR UC
Recruiting Phase 2
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Summary
This is a phase 2b, randomized, double-blind, 3-arm study for the treatment of Ulcerative Colitis. The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Ulcerative Colitis. The total study duration is up to 168 weeks, with a treatment period of up to 158 weeks including an open-label (OL) long-term extension (LTE) period of up to 104 weeks for eligible participants.
Protocol Amendment History 15 amendments
This ClinicalTrials.gov record has been amended 15 times since 2025-05-08; most recent amendment 2026-04-22.
Status change: Not Yet Recruiting → Recruiting 2025-07-03
Trial Details
NCT Number NCT06975722
Lead Sponsor Sanofi
Conditions Ulcerative Colitis
Enrollment 99 participants
Start Date 2025-07-07
Primary Completion 2026-12-17 (estimated)
Study Completion 2029-10-17 (estimated)
Updated on ClinicalTrials.gov 2026-04-23