Clinical Trial

Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung Cancer

Study acronym: NSCLC
Recruiting Phase 3
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Summary
This is a Phase 3 Randomized, double-blind, Multicenter Study of Ivonescimab Combined with Docetaxel Versus Placebo Combined with Docetaxel in Patients with Locally advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) that has progressed on or after PD-(L)1 inhibitor-based therapy. The purpose of this study is to evaluate the efficacy and safety of ivonescimab versus placebo, combined with docetaxel in patients with advanced NSCLC.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-08; most recent amendment 2026-04-07.
Status change: Not Yet Recruiting → Recruiting 2026-04-07
Trial Details
NCT Number NCT06928389
Lead Sponsor Akeso
Conditions Non-Small Cell Lung Cancer
Enrollment 536 participants
Start Date 2025-07-08
Primary Completion 2027-05 (estimated)
Study Completion 2030-06 (estimated)
Updated on ClinicalTrials.gov 2026-04-09