Clinical Trial

Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery

Study acronym: CLOSURE
Not Yet Recruiting
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Record status
This record was last updated April 9, 2025 (before its estimated March 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a prosthetic or biologic graft, patch, or allograft. The effectiveness of the adhesive will be assessed after restoring blood flow.
Trial Details
NCT Number NCT06918496
Lead Sponsor Grena Biomed Limited
Collaborators: Archer Research
Conditions Aortic Aneurysm, Aortic Aneurysm Abdominal, Valve Stenoses, Aortic, Valve Regurgitation, Mitral, Valve Regurgitation, Tricuspid, Aneurysm of Ascending Aorta, Aneurysm Abdominal, Artery Diseases, Peripheral +6 more
Enrollment 60 participants
Start Date 2025-06-30
Primary Completion 2026-03-31 (estimated)
Study Completion 2026-03-31 (estimated)
Updated on ClinicalTrials.gov 2025-04-09