Adaptation and Normalization of a Verbal Episodic Memory Test in French Sign Language

Study acronym: RL-RI-LSF
StatusSuspended
PhaseNot applicable
Started

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Record History

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  1. Stopped Trial status changed: Not Yet Recruiting → Suspended Sponsor's reason: Inclusions suspended during the period between phase 1 (adaptation of the test in French sign Language) and phase 2 (inclusion for the standardization of the test). Show 9 more changesShow less
    • Primary completion pushed from Jan 2027 to Nov 2027
    • Primary endpoint(s) modified
    • Study completion pushed from Apr 2027 to Aug 2028
    • Interventions modified
    • Study sites: 0 to 1
    • Start date changed from estimate of Apr 2025 to May 5, 2025
    • Eligibility criteria expanded, about 9 words
    • Secondary endpoints revised (4)
    • Study description expanded, about 142 words
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
To date, neuropsychological assessment of deaf signing persons is complicated by a lack of resources, especially the absence of tools available in French Sign Language (LSF). This is due to perceptual and cultural differences, and in particular the linguistic differences between French and LSF. This lack of resources significantly hinders access to care for deaf patients, as neuropsychological assessment is often a key clinical criterion in the diagnosis of certain neurological pathologies (Alzheimer's disease in particular) and enables coherent care plans to be drawn up, for example in the aftermath of strokes or traumatic brain injuries. In particular, episodic memory (which refers to the ability to memorise information anchored in a specific context) is a cognitive domain that is sensitive to pathologies such as Alzheimer's disease, but it is not currently possible to assess it with deaf signing patients. The aim of this study is to create a memory assessment test adapted to a deaf population that expresses in LSF and to normalize this test on this same population. The aim is to provide a diagnosis assessment tool, which currently does not exist in France, to improve access to care for deaf people. This project could then be extended to the creation of tests for other cognitive domains (executive functions, attention, social cognition, etc.) and to prospects for cognitive remediation. The 16-item Free and Cued Recall test (RL-RI 16) is the best choice because it is easy to use and accurate enough to assess each stage of episodic memory. These qualities make it a decisive tool in certain differential diagnosis.
Trial Details
NCT Number NCT06902753
Lead Sponsor Poitiers University Hospital
Conditions
(from sponsor)
Neuropsychological Tests, Memory, Alzheimer Disease, Deafness, Sign Language, Cognitive Impairment
Related terms Alzheimer Disease, Cognitive Dysfunction, Deafness, Sign Language
Enrollment 120 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov