Clinical Trial

GLP-1s to Enhance Lasting Optimal Weight

Study acronym: GLOW
Active, Not Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The goal of this study is to examine how tirzepatide affects body composition, bone health, and physical performance in older adults over a nine-month period. Participants will take tirzepatide weekly, have clinic visits every 4 weeks, meet study doctor and registered dietitian every 4 weeks in person or video conference, attend group intervention sessions twice a month via video conference, weigh daily with a study-provided smart scale, keep a record of all foods and beverages consumed, and use a study-provided activity tracker to keep track of daily step counts.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2025-02-28; most recent amendment 2025-10-27.
Status change: Recruiting → Active, Not Recruiting 2025-10-27
Status change: Not Yet Recruiting → Recruiting 2025-06-23
Trial Details
NCT Number NCT06861439
Lead Sponsor Wake Forest University Health Sciences
Conditions Obesity
Enrollment 40 participants
Start Date 2025-07-07
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-10-28