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Longitudinal Study of the GLUcagon REsponse to Hypoglycemia in Children and Adolescents With New-onset Type 1 DIAbetes

Study acronym: GLUREDIA
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated January 13, 2025 (before its estimated October 25, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
The GLUREDIA study investigates the counter-regulatory response (CRR) during hypoglycemia in children with type 1 diabetes (T1D). Hypoglycemia can lead to severe symptoms, but is normally counteracted by CRR, corresponding to the secretion of hormones to maintain normoglycemia. Hypoglycemia is common in T1DM but some patients develop severe hypoglycemia as a result of CRR dysfunction. Despite several studies in adults, the presence of CRR dysfunction remains unpredictable and not well understood. The objective of GLUREDIA is therefore to describe and predict the evolution of CRR in children with T1DM.
Trial Details
NCT Number NCT06770621
Lead Sponsor Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Collaborators: The Leona M. and Harry B. Helmsley Charitable Trust
Conditions
(from sponsor)		 Severe Hypoglycemia, Type1diabetes
Related terms Diabetes Mellitus, Hypoglycemia
Enrollment 1,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov