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Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease

StatusRecruiting
PhaseNot applicable
Started2025-08-01
View on ClinicalTrials.gov ↗

Amendment history

2026-03-25
notable
Not Yet Recruiting→Recruiting Study Status, Sponsor/Collaborators, Arms and Interventions, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2027-03-01→2027-12-01
Completion date2027-07-01→2027-12-01
Start dateestimated 2025-03-01→confirmed 2025-08-01
Study sites0→1
2024-12-12
minor
Study Status, Sponsor/Collaborators, Oversight, Conditions, Outcome Measures v1
Secondary endpointsdetails revised at 1 of 6 entries
2024-12-09
minor
Original filing
Alzheimer's disease is a neurodegenerative condition that affects both cognitive and motor functions, making daily life activities more challenging. Motor functions, especially walking and balance, begin to deteriorate early in the disease and progress in parallel with cognitive decline. Dual-task performance, which refers to the ability to perform both motor and cognitive tasks simultaneously, significantly decreases in individuals with Alzheimer's disease. Current studies suggest that dual-task exercises can improve both cognitive and motor functions. In this context, treadmill-based dual-task training emerges as a promising approach to mitigate the effects of Alzheimer's disease. The study hypothesizes that treadmill-based dual-task training will have more positive effects on motor and cognitive parameters compared to treadmill exercise alone in individuals with Alzheimer's disease. The main research question of this study is whether treadmill-based dual-task exercise training, designed with progressively more challenging cognitive and motor tasks and tailored to the individual, results in significant improvements in motor and cognitive parameters, as well as daily living activities and dual-task performance, compared to a group that only undergoes treadmill exercise.
Trial Details
NCT Number NCT06731049
Lead Sponsor Istanbul University - Cerrahpasa
Conditions Alzheimer' Disease, Dementia
Enrollment 46 participants
Start Date 2025-08-01
Primary Completion 2027-12-01 (estimated)
Study Completion 2027-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-03-31