Clinical Trial

Thermotherapy in Addition to SOC Palliative Radiotherapy

Study acronym: ThermoRad wIRA
Recruiting
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Summary
This study aims to investigate the efficacy and safety profile of superficial hyperthermia (wIRA) in addition to standard of care (SOC) palliative radiotherapy in patients with inoperable/incurable locally advanced or recurrent/metastatic HNSCC or cutaneous SCC superficial tumours not suitable for radical treatment. The investigators will assess the best objective response rate (ORR) of patients with Inoperable/incurable or recurrent/metastatic HNSCC or cSCC with superficial lesion(s) treated with the combination of superficial hyperthermia (wIRA) and palliative radiotherapy.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-10-23; most recent amendment 2025-12-15.
Status change: Active, Not Recruiting → Recruiting 2025-08-26
Trial Details
NCT Number NCT06659146
Lead Sponsor King's College London
Collaborators: Guy's and St Thomas' NHS Foundation Trust
Conditions Head and Neck Squamous Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, Breast Cancer Recurrent
Enrollment 60 participants
Start Date 2024-10-14
Primary Completion 2028-03-01 (estimated)
Study Completion 2028-03-01 (estimated)
Updated on ClinicalTrials.gov 2025-12-22