Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06458036 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Study acronym: RAISE
StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Study sites: 4 to 5v8
  2. Study sites: 2 to 4v7
  3. Re-verified, no change to tracked fieldsv6
  4. Study sites: 1 to 2
    • Eligibility criteria expanded, about 3 words
    v5
  5. Re-verified, no change to tracked fieldsv4
Show 2 earlier versionsHide 2 earlier versions
  1. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    • Start date changed from estimate of Nov 1, 2024 to Jul 29, 2024
    v3
  2. Start date: Aug 1, 2024 to Nov 1, 2024
    • Primary completion date: Aug 1, 2030 to Nov 1, 2030
    • Study completion date: Aug 1, 2031 to Nov 1, 2031
    v2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy. However, less than a quarter of patients with lung metastases will achieve a complete response to RAI therapy, and this therapy carries the risk of pulmonary fibrosis and an increasingly recognized risk of secondary malignancies.
Trial Details
NCT Number NCT06458036
Lead Sponsor Children's Hospital of Philadelphia
Collaborators: Eli Lilly and Company, United States Department of Defense
Conditions
(from sponsor)		 Differentiated Thyroid Cancer, Pediatric Cancer, Cancer, Cancer, Thyroid
Related terms Neoplasms, Thyroid Neoplasms
Enrollment 13 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov