Clinical Trial

Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications

Recruiting Phase 4
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Summary
Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2024-05-02; most recent amendment 2025-09-03.
Status change: Not Yet Recruiting → Recruiting 2024-08-20
Trial Details
NCT Number NCT06401642
Lead Sponsor Mayo Clinic
Conditions Migraine
Enrollment 200 participants
Start Date 2024-03-22
Primary Completion 2027-03 (estimated)
Study Completion 2027-03 (estimated)
Updated on ClinicalTrials.gov 2025-09-09