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Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC

StatusRecruiting
PhasePhase 2
Started2023-12-14
View on ClinicalTrials.gov ↗

Amendment history

2026-03-31
Study Status, Study Design, Contacts/Locations v10
Trial status changed: Active, Not Recruiting → Recruiting
Enrollment increased: 25 → 35 participants
Primary completion pushed: 2026-11 → 2027-05
Completion pushed: 2026-11 → 2027-05
Study sitesdetails revised at 1 of 1 site
2026-01-27
Study Status v9
Re-verified, no change to tracked fields
2025-12-30
Study Identification, Study Status, Oversight, Study Design v8
PhaseNot applicable→Phase 2
Study title+2 characters
PilotPhase 2 Trial of Adaptive Radiotherapy Boost for HNSCC
2025-10-16
Recruiting→Active, Not Recruiting Study Status, Study Design, Contacts/Locations v7
Trial statusRecruiting→Active, Not Recruiting
Primary completion date2025-10→2026-11
Completion date2026-10→2026-11
Study sitesdetails revised at 1 of 1 site
2025-06-16
Study Status, Oversight v6
Re-verified, no change to tracked fields
Show 5 earlier versions
2025-03-14
Study Status v5
Start date2023-12-18→2023-12-14
2024-12-10
Study Status v4
Re-verified, no change to tracked fields
2024-08-21
Study Status, Contacts/Locations v3
Primary completion date2027-01→2025-10
Completion date2027-01→2026-10
Study sitescontacts updated at 1 of 1 site
2024-03-21
Study Status v2
Start date2023-10-26→2023-12-18
2023-12-19
Study Identification, Study Status, Arms and Interventions, Eligibility v1
Eligibility criteria-126 characters
[...] uations that would limit compliance with study requirements. Unable to undergo MRIs or has contraindications to undergoing MRIs (pacemaker, neural stimulator, MR-incompatible metal, etc.
Study title-10 characters
Pilot Trial of MR-guided Adaptive Radiotherapy Boost for HNSCC
2023-11-13
Original filing
The purpose of the study is to determine if it is feasible to use magnetic resonance imaging (MRI) to adjust a portion of radiation therapy for patients with head and neck squamous cell carcinoma . The technique under study will be used to personalize the study treatment based on response, keeping all treatments within standard of care guidelines.
Trial Details
NCT Number NCT06137274
Lead Sponsor H. Lee Moffitt Cancer Center and Research Institute
Conditions Squamous Cell Carcinoma, Head and Neck Cancer
Enrollment 35 participants
Start Date 2023-12-14
Primary Completion 2027-05 (estimated)
Study Completion 2027-05 (estimated)
Updated on ClinicalTrials.gov 2026-04-01