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Pilot Window of Opportunity Trial (POET)

StatusActive, Not Recruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Study completion pushed from Jun 30, 2026 to Sep 30, 2026v9
  2. Trial status: Recruiting to Active, Not Recruiting
    • Primary completion date changed from estimate of Dec 30, 2025 to Aug 22, 2025
    • Study completion date: Sep 30, 2026 to Jun 30, 2026
    • Site details revised
    v8
  3. Primary completion date: Sep 30, 2025 to Dec 30, 2025v7
  4. Primary completion date: Apr 30, 2025 to Sep 30, 2025
    • Study completion date: Apr 30, 2026 to Sep 30, 2026
    v6
  5. Start date changed from estimate of Apr 30, 2024 to Apr 3, 2024v5
Show 3 earlier versionsHide 3 earlier versions
  1. Primary completion date: Apr 2025 to Apr 30, 2025
    • Study completion date: Apr 2026 to Apr 30, 2026
    • Start date: Apr 2024 to Apr 30, 2024
    v4
  2. Primary completion date: Mar 2025 to Apr 2025
    • Study completion date: Mar 2026 to Apr 2026
    • Start date: Mar 2024 to Apr 2024
    v3
  3. Trial status: Not Yet Recruiting to Recruitingv2 Show 5 more changesShow less
    • Start date: Jan 2024 to Mar 2024
    • Primary completion date: Jan 2025 to Mar 2025
    • Study completion date: Jan 2026 to Mar 2026
    • Eligibility criteria expanded, about 58 words
    • Study site revised
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The proposed clinical trial with TPST-1495 can help people with two types of cancer, Endometrial Cancer (EC) and Colorectal Carcinoma (CRC), who need surgery. The investigator plans to evaluate how well TPST-1495 works against these cancers by checking blood samples and tumor tissues taken before and after the treatment to see if it is an effective treatment option to help the immune system fight against cancer.
Trial Details
NCT Number NCT06129604
Lead Sponsor University of Oklahoma
Conditions
(from sponsor)		 Colorectal Carcinoma (CRC), Endometrial Carcinoma (EC)
Related terms Colorectal Neoplasms, Endometrial Neoplasms
Enrollment 10 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov