Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05927090 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial
NCT05927090 · ClinicalTrials.gov record · last posted 2026-05-19

Outcomes of Aortic Dissection Repair

Study acronym: STAAD
StatusEnrolling by Invitation
PhaseNot specified
Started2005-01-01
View on ClinicalTrials.gov ↗
from the ClinicalTrials.gov record
Type A aortic dissection (TAAD) is a potentially life-threatening pathology associated with significant risk of mortality and morbidity. In acute forms of type A aortic dissection (TAAD) mortality is 50% by 24 h and 50% of patients die before reaching a specialist center. Rapid diagnosis and subsequent prompt surgical repair remain the primary goal for these patients. In the last decade it has been observed that improvements in diagnostic techniques, initial management and increased clinical awareness have contributed to a substantial increase in the number of patients benefiting from a prompt diagnosis and undergoing surgery.However, survival after surgical repair has not yet reached optimal follow-ups and is burdened by high in-hospital mortality(16-18%)The main approach to acute type B non-complicated aortic dissection (TBAD) has always been to use medicines to control the patient's heart rate and blood pressure. However, recent findings suggest that a large number of patients treated for acute complicated (TBAAD) and non-complicated TBAD experience aortic complications, such as aneurysmal degeneration, at a later stage.

Amendment record 7 amendments on the ClinicalTrials.gov record

This ClinicalTrials.gov record has been amended 7 times since 2023-06-23; most recent amendment 2026-05-16. DataLookout shows field-level changes from the day a trial enters its daily monitoring; earlier amendments are counted here from the ClinicalTrials.gov version history. See every version on ClinicalTrials.gov ↗

Trial Details
NCT Number NCT05927090
Lead Sponsor Centre Cardiologique du Nord
Collaborators: Henri Mondor University Hospital, Universita degli Studi di Genova, Pitié-Salpêtrière Hospital, Ospedale San Camillo, Rome, Italy, Campus Bio-Medico University
Conditions Type A Aortic Dissection, Ascending Aortic Dissection, Aortic Diseases, Aortic Arch, Aortic Valve Insufficiency, Aortic Root Dissection, Aortic Root Dilatation, Type B Aortic Dissection
Enrollment 1,200 participants
Start Date 2005-01-01
Primary Completion 2021-12-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-19