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Diaphragmatic Function as a Biomarker

Study acronym: DFUNBIO
StatusRecruiting
PhaseNot specified
Started
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Record History

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  1. Notable Primary and study completion dates: Jun 30, 2025 to Dec 30, 2026
    • Study description expanded, about 67 words
    v3
  2. Notable Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 0 to 1
    v2
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
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Dyspnea is among the most common symptoms in patients with respiratory diseases such as Asthma, chronic obstructive pulmonary disease (COPD), Fibrosis, and Pulmonary Hypertension. However, the pathophysiology and underlying mechanisms of dyspnea in patients with respiratory diseases are still poorly understood. Diaphragm dysfunction might be highly prevalent in patients with dyspnea and respiratory diseases. The association of diaphragm function and potential prognostic significance in patients with respiratory diseases has not yet been investigated.
Trial Details
NCT Number NCT05903001
Lead Sponsor RWTH Aachen University
Conditions
(from sponsor)
Dyspnea; Asthmatic, COPD, Fibrosis, Pulmonary Hypertension, Asthma, Dyspnea
Related terms Asthma, Dyspnea, Fibrosis, Hypertension, Pulmonary, Pulmonary Disease, Chronic Obstructive
Enrollment 800 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov