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A Closed Loop, Doctor to Patient, Mobile Application for Depression in People With Multiple Sclerosis

Study acronym: MS-CATCH
StatusActive, Not Recruiting
PhaseNot applicable
Started2023-08-01
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 5 months later Aug 15, 2026 → Jan 15, 2027
See other at-risk trials from University of California, San Francisco

Amendment history

2026-09-10
Study Status v7
Primary completion pushed: 2026-08-15 → 2027-01-15
Completion pushed: 2026-08-15 → 2027-01-15
2025-10-13
Recruiting→Active, Not Recruiting Study Status, Contacts/Locations v6
Trial statusRecruiting→Active, Not Recruiting
Primary completion date2025-05-15→2026-08-15
Completion date2025-05-15→2026-08-15
Study sitesdetails revised at 1 of 1 site
2024-02-16
Study Status, Outcome Measures v5
Secondary endpoints13 entries, revised
Other self-reported outcome - MFISModified Fatigue Impact Scale - Exploratory Other self-reported outcome - PSQIPittsburgh Sleep Quality Index - Exploratory Other self-reported outcome - OxOxford-PAQParticipation and Activities Questionnaire - Exploratory Other self-reported outcome - IPAImpact on Participation and Autonomy - Exploratory
2024-02-05
Study Status, Outcome Measures v4
Secondary endpoints2 to 13 entries
ChangeMood in HADS-D (Hospital Anxiety and Depression Screenerscores - Depression)Primary TheMood amountscores of- participantsExploratory Mood thatscores stay- activeExploratory Other inself-reported theoutcome study- MFIS - Exploratory Other self-reported outcome - PSQI - Exploratory Other self-reported outcome - Ox-PAQ - Exploratory Other self-reported outcome - IPA - Exploratory Engagment (trialSustained retentionuse) - Secondary Engagement (Sustained use) - Secondary Engagement (Sustained use) - Exploratory Engagement (Sustained use) - Exploratoy Engagement (Sustained use) - Exploratory A [...]
Primary endpoints14 to 7 entries
Change in clinician screening of depression: Arm 1 vs Arm 2 Change in clinician screening of depression: Arm 1 vs Arm 2 Clinician comprehensive depression evaluation Percentage of participants who respond to mental health promptsAdoption (Adherenceuptake) - Primary Percentage of patient-clinician encounters that initially use the toolAdoption (adoptionuptake) - Secondary PercentageComprehensive ofMood patientEvaluation -clinician encountersSecondary Mood whoReporting use- theSecondary Mood toolScreening during- thePrimary Treatment 12 month visit (Engagement) Percentage of patients initially u [...] [...]
2023-11-21
Study Status, Eligibility v3
Eligibility criteria+236 characters
[...] Exclusion Criteria: Cognitive dexterity or visual impairment (typically defined as corrected acuity less than 20/70) that, in the opinion of the study neurologist (RB), would p [...] s: bipolar disorder, schizophrenia, schizoaffective disorder Substance abuse that in the treating neurologist's perspective could influence the patient's safety on study or adherence to study protocol Another co-morbid CNS diagnosis eg. TBI
Show 2 earlier versions
2023-08-10
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2023-07-10→confirmed 2023-08-01
Study sitesdetails revised at 1 of 1 site
2023-06-26
Study Status v1
Start date2023-05-15→2023-07-10
2023-05-09
Original filing
The researchers want to find out if an electronic application called MS CATCH can enhance patients' and doctors' experiences during and in between clinical visits. MS CATCH is a smartphone-based tool which allows patients to enter their mood related symptoms at regular intervals, which is then available to their Neurologist in their electronic medical record. The neurologist is also able to view additional information from their medical record, and receives alerts for changes reported by the patient that raise concern for the patient's mental health.
Trial Details
NCT Number NCT05865405
Lead Sponsor University of California, San Francisco
Collaborators: United States Department of Defense
Conditions Multiple Sclerosis, MS, Depression
Enrollment 100 participants
Start Date 2023-08-01
Primary Completion 2027-01-15 (estimated)
Study Completion 2027-01-15 (estimated)
Updated on ClinicalTrials.gov 2026-09-14