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NCT05786274 · ClinicalTrials.gov record · last posted 2026-07-06

Predicting Cerebrovascular Adverse Events Post Cardiac Surgery

Study acronym: PASCAL
StatusRecruiting
PhaseNot applicable
Started2023-04-01
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from the ClinicalTrials.gov record
The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via cerebral blood flow velocity estimated by transcranial Doppler device with simpler measurements derived from near infrared spectroscopy; iii) to develop a predictive model of postoperative cerebrovascular outcome (overt or silent stroke) based on the extracted indices.

Amendment record 3 amendments on the ClinicalTrials.gov record

This ClinicalTrials.gov record has been amended 3 times since 2023-03-15; most recent amendment 2026-07-02. DataLookout shows field-level changes from the day a trial enters its daily monitoring; earlier amendments are counted here from the ClinicalTrials.gov version history. See every version on ClinicalTrials.gov ↗

2023-11-06
Status change Not Yet Recruiting→Recruitingv1
Trial Details
NCT Number NCT05786274
Lead Sponsor IRCCS Policlinico S. Donato
Collaborators: University of Milan
Conditions Cardiac Disease
Enrollment 104 participants
Start Date 2023-04-01
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-06