Predicting Cerebrovascular Adverse Events Post Cardiac Surgery

The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via cerebral blood flow velocity estimated by transcranial Doppler device with simpler measurements derived from near infrared spectroscopy; iii) to develop a predictive model of postoperative cerebrovascular outcome (overt or silent stroke) based on the extracted indices.

NCT Number	NCT05786274
Lead Sponsor	IRCCS Policlinico S. Donato Collaborators: University of Milan
Conditions	Cardiac Disease
Enrollment	104 participants
Start Date	2023-04-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-06