Clinical Trial

REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)

Study acronym: REINVENT
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
Primary Objective - To determine if implantation of a permanent CRT pacing device (with LB-CRT, or conventional BiV-CRT with a coronary sinus LV lead) can improve electromechanical function, HF symptoms, and natriuretic peptide levels among patients with symptomatic HF, LVEF \> 35%, and LBBB.
Protocol Amendment History 1 change
minor Completion pushed: 2026-03-31 -> 2026-09-30 2026-05-07
Trial Details
NCT Number NCT05652218
Lead Sponsor Inova Health Care Services
Collaborators: Medtronic
Conditions Left Ventricular Ejection Fraction, Heart Failure (HF), Left Bundle-Branch Block
Enrollment 21 participants
Start Date 2023-02-26
Primary Completion 2026-02-28 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-06