Dietary Counseling Coupled With FMT in the Treatment of Obesity and NAFLD - the DIFTOB Study

There are several studies performed to reveal the linkage between diet, fecal microbiota, and obesity. Human fecal microbiota transplantations in this asset are still scarce. Therefore, this pilot study of FMT from lean to obese people with dietary counseling will increase the knowledge, whether FMT could play a role in the treatment of obesity and NAFLD. Our primary outcome is the changes in glucose metabolism by HOMA-IR.

NCT Number	NCT05607745
Lead Sponsor	University of Eastern Finland Collaborators: Helsinki University Central Hospital, Päijänne Tavastia Central Hospital, University of Helsinki, Kuopio University Hospital, Kuopio Research Institute of Exercise Medicine
Conditions	NAFLD, Fecal Microbiota, Gut Microbiota, Obesity, Dietary Habits, Diet, Fecal Microbiota Transplantation, Glucose Metabolism Disorders +1 more
Enrollment	54 participants
Start Date	2022-10-30
Primary Completion	2024-06 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2022-11-07