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Targeting Specific Brain Networks to Treat Specific Symptoms in Depression

StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 5 months later Dec 31, 2027 → May 31, 2028
See other at-risk trials from Massachusetts General Hospital

Record History

  1. Primary completion pushed from Dec 31, 2027 to May 31, 2028 Completion pushed from Dec 31, 2028 to May 31, 2029 · Eligibility criteria expanded, about 15 words · Site contact updated · 1 more Show 4 more changesShow less
    • Completion pushed from Dec 31, 2028 to May 31, 2029
    • Eligibility criteria expanded, about 15 words
    • Site contact updated
    • Publications: details revised at 2 of 2 entries
  2. Site contact updatedv5
  3. Trial status: Not Yet Recruiting to Recruiting Start date changed from estimate of Dec 1, 2023 to Mar 12, 2024 · Site details revisedv4 Show 2 more changesShow less
    • Start date changed from estimate of Dec 1, 2023 to Mar 12, 2024
    • Site details revised
  4. Start date: Aug 1, 2023 to Dec 1, 2023v3
  5. Start date: Jan 2, 2023 to Aug 1, 2023 Collaborators expanded, about 6 wordsv2 Show 1 more changeShow less
    • Collaborators expanded, about 6 words

    See this version in full on ClinicalTrials.gov ↗

  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Repetitive transcranial magnetic stimulation (rTMS) is a way of non-invasively stimulating specific brain networks and is an established treatment for Major Depressive Disorder (MDD). This proposal will reveal network mechanisms of the therapeutic effects of rTMS by investigating how stimulating each network specifically changes network connectivity and behavior. This will be done in a highly individualized manner in depressed and healthy patients, leading to more effective and more individualized treatments for depression.
Trial Details
NCT Number NCT05523817
Lead Sponsor Massachusetts General Hospital
Collaborators: National Institute of Mental Health (NIMH)
Conditions Major Depressive Disorder
Enrollment 80 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov