Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05459077 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

StatusNot Yet Recruiting
PhaseNot applicable
Started2026-12-03
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 4 months later across 2 updates Jul 31, 2026 → Dec 30, 2026
See other at-risk trials from Duke University

Amendment history

2026-10-02
notable
Primary completion pushed: 2026-09-30 → 2026-12-30
Completion pushed: 2026-09-30 → 2026-12-30
2026-07-22
notable
Study Status, Contacts/Locations v7
Primary completion pushed: 2026-07-31 → 2026-09-30
Start date2026-04-20→2026-09-03
Study sitescontacts updated at 1 of 1 site
2026-03-25
minor
Study Status, Outcome Measures v6
Start date2025-11-20→2026-04-20
Secondary endpointsdetails revised at 4 of 6 entries
2025-10-21
minor
Study Status v5
Start date2025-10-01→2025-11-20
2025-07-22
notable
Recruiting→Not Yet Recruiting Study Status, Contacts/Locations v4
Trial statusRecruiting→Not Yet Recruiting
Primary completion date2026-05→2026-07-31
Completion date2026-05→2026-09-30
Start date2022-08-01→2025-10-01
Study sitesdetails revised at 1 of 1 site
Show 3 earlier versions
2024-10-18
minor
2 amendments v2-v3
2 re-verifications since 2023-07-11, no change to tracked fields
2022-08-04
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Start dateestimated 2022-07→confirmed 2022-08-01
Study sites0→1
2022-07-13
minor
Original filing
455 trials monitored
See 53 trials at risk
1,786 trials monitored
See 77 trials at risk
Among those with hypertension, persons living with HIV (PWH) have a 50% higher risk of incident myocardial infarction compared to the general population, and they often fail to meet evidence-based treatment goals for hypertension. An important contributing factor for insufficient blood pressure control is non-adherence to antihypertensive medications. Research on medication adherence for PWH has largely focused on antiretroviral therapy adherence with limited focus on adherence to other non-AIDS condition medications. With a large proportion of PWH in the U.S. achieving viral suppression, providers may now have an opportunity to focus on the management of non-AIDS conditions like hypertension. However, because PWH who have achieved suppression have reduced clinic encounters (once or twice a year) there is potential loss of opportunity to effectively monitor and intensify hypertension treatment as needed an important opportunity to focus on preventing cardiovascular disease. CVD and other non-AIDS comorbidities. The study's overarching goal is to improve the hypertension outcomes for PWH on suppressive ART to reduce cardiovascular disease risk. In this study, we will identify and evaluate healthcare and patient-level factors that must be addressed in an intervention to increase hypertension medication adherence for PWH who have achieved viral suppression. We will use these factors to tailor an intervention and assess the feasibility and acceptability at the Duke ID clinic.
Trial Details
NCT Number NCT05459077
Lead Sponsor Duke University
Conditions Hypertension, HIV-1-infection
Enrollment 60 participants
Start Date 2026-12-03
Primary Completion 2026-12-30 (estimated)
Study Completion 2026-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-10-01