Clinical Trial

PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

Recruiting Phase 3
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Summary
The investigators will compare \[18F\]-PI-2620 tau PET scans from patients with frontotemporal lobar degeneration (FTLD), patients with non-amnestic presentations of Alzheimer's disease (naAD), and demographically matched cognitively normal subjects.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2022-07-08; most recent amendment 2025-11-03.
Status change: Not Yet Recruiting → Recruiting 2022-10-12
Trial Details
NCT Number NCT05456503
Lead Sponsor University of Pennsylvania
Collaborators: National Institutes of Health (NIH)
Conditions Frontotemporal Lobar Degeneration, Alzheimer Disease, Cognitively Normal
Enrollment 72 participants
Start Date 2022-09-19
Primary Completion 2028-08 (estimated)
Study Completion 2028-08 (estimated)
Updated on ClinicalTrials.gov 2025-11-04