Clinical Trial

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

Study acronym: SELECT
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT), compared to the usual treatment when radiotherapy is given to both sides of the neck?
Protocol Amendment History 1 change
notable Trial sites expanded: 33 -> 36 locations 2026-04-15
Trial Details
NCT Number NCT05451004
Lead Sponsor Canadian Cancer Trials Group
Collaborators: Alliance for Clinical Trials in Oncology, Eastern Cooperative Oncology Group, NRG Oncology, SWOG Cancer Research Network
Conditions Oropharyngeal Cancer
Enrollment 510 participants
Start Date 2023-02-10
Primary Completion 2030-08-30 (estimated)
Study Completion 2031-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-14