Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT05294107 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Intestinal Organoids

Study acronym: BIOÏDES
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

  1. Primary and study completion pushed from Dec 2026 to Mar 7, 2028
    • Trial status changed: Active, Not Recruiting → Recruiting
    • Site details revised
    v7
  2. Primary and study completion dates: Mar 2026 to Dec 2026
    • Trial status: Recruiting to Active, Not Recruiting
    • Site details revised
    v6
  3. Primary and study completion dates: Sep 2024 to Mar 2026v5
  4. Re-verified, no change to tracked fieldsv4
  5. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Apr 2022 to Sep 6, 2022
    • Primary and study completion dates: Apr 2024 to Sep 2024
    • Site details revised
    v3
  6. Re-verified, no change to tracked fieldsv2
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Over the last decade, the use of mini-organ or organoids has been increasingly developed in fundamental research. Indeed, digestive organoids represent an essential advance compared to classical culture systems (epithelial cell lines, immortalized cells) since they preserve in culture the functional complexity present in vivo (architecture, different cell types). They also have the advantage of being able to be propagated indefinitely (unlike explants), minimizing the use of animal models and reducing the amount of tissue required. Finally, their growth and development depends on the origin of the sample (the organoid will develop differently if the cell source comes from a patient suffering from an inflammatory bowel disease, for example), thus generating models of human pathologies to better determine their physiopathology. The use of organoids in biomedical research has proven to be an indispensable tool for the understanding of cellular and molecular mechanisms involved in epithelial renewal and the screening of molecules and ingredients for applications in the health and agri-food sectors.
Trial Details
NCT Number NCT05294107
Lead Sponsor Rennes University Hospital
Conditions
(from sponsor)		 Digestive System Diseases, Inflammatory Bowel Disease, Ulcerative Colitis Type, Crohn Disease
Related terms Colitis, Ulcerative, Crohn Disease, Digestive System Diseases, Inflammatory Bowel Diseases
Enrollment 90 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov