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Neuroplasticity in Parkinson's Disease

StatusCompleted
PhaseNot specified
Started
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Record History

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  1. Trial completed
    • Final enrollment: 26 participants (planned 50)
    • Primary and study completion dates changed from estimate of Aug 31, 2026 to Aug 25, 2026
    • Eligibility criteria expanded, about 18 words
  2. Re-verified, no change to tracked fieldsv8
  3. Trial status: Recruiting to Active, Not Recruiting
    • Primary completion date: Jul 9, 2026 to Aug 31, 2026
    • Study completion date: Nov 9, 2028 to Aug 31, 2026
    • Site details revised
    v7
  4. Primary completion date: Jul 9, 2025 to Jul 9, 2026v6
  5. Eligibility criteria expanded, about 16 wordsv5
  6. 3 versions Re-verified since Mar 20, 2023, no change to tracked fieldsv2-v4
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of this project is to increase our understanding of the early state and temporal evolution of neuroplastic changes in the cortex and subthalamic nucleus (STN) of people with PD, and the relationship of these changes to the emergence and expression of PD motor and non-motor signs. Neurophysiological biomarkers derived from this work may be important for the early detection and prediction of progression of disease. They can also provide the means to assess the efficacy of interventions designed to prevent or slow disease progression.
Trial Details
NCT Number NCT05286736
Lead Sponsor University of Minnesota
Conditions
(from sponsor)		 Parkinson, Parkinson Disease
Related terms Parkinson Disease
Enrollment 26 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov